Clinical Challenges in Nonfunctional Pheochromocytomas
نویسندگان
چکیده
منابع مشابه
Pheochromocytomas and Paragangliomas: Clinical and Genetic Approaches
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are neuroendocrine tumors derived from the chromaffin tissue. Diagnosis of these tumors is extremely important as they are linked to the hypertension syndrome with great cardiovascular morbidity and mortality. A great majority of PCCs and PGLs are sporadic and benign tumors; however, the classic idea of 10% exception of these features is changi...
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.........................................................................................................................................................10 INTRODUCTION................................................................................................................................................11 REVIEW OF THE LITERATURE.............................................................
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Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare neuroendocrine tumors of the adrenal glands and the sympathetic and parasympathetic paraganglia. They can occur sporadically or as a part of different hereditary tumor syndromes. About 30% of PCCs and PGLs are currently believed to be caused by germline mutations and several novel susceptibility genes have recently been discovered. The...
متن کاملClinical and Pathological Characteristics of Hypertensive and Normotensive Adrenal Pheochromocytomas.
INTRODUCTION Pheochromocytoma/Paraganglioma (PPGL) present with an extremely variable clinical picture which ranges from dramatic, to mild, to silent, depending on tumor attitude to release catecholamines. Hypertension is the hallmark of these tumors but is not always present. Distinct differences of clinical manifestations exist in hypertensive pheochromocytomas (HPs) and normotensive pheochro...
متن کاملA clinical scoring system for detection of patients with pheochromocytomas.
We analyzed the medical records of patients admitted to 11 hospitals over a 15-year period, looking for those with metabolically active sporadic pheochromocytomas (Group A) and those in whom the diagnosis was highly suspect but excluded (Group B). Fifty-three patients in Group A and 25 patients in Group B were found. We then devised a scoring system based on the presence or absence of typical s...
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ژورنال
عنوان ژورنال: World Journal of Endocrine Surgery
سال: 2019
ISSN: 0975-5039,0975-7902
DOI: 10.5005/jp-journals-10002-1264